Membrane Potential of Weak Amphoteric Polymer Membrane Composed of Silk Fibroin.
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چکیده
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The pharmaceutical utility of silk fibroin (SF) materials for drug delivery was investigated. SF films were prepared from aqueous solutions of the fibroin protein polymer and crystallinity was induced and controlled by methanol treatment. Dextrans of different molecular weights, as well as proteins, were physically entrapped into the drug delivery device during processing into films. Drug relea...
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OBJECTIVES/HYPOTHESIS To evaluate the efficacy of silk fibroin scaffolds (SFS) and acellular collagen scaffolds (ACS) for the repair of tympanic membrane (TM) in a guinea pig acute perforation model. STUDY DESIGN Experimental animal research. METHODS Seventy-two albino guinea pigs underwent perforation of the right TM and were divided into four experimental groups (n = 18). The perforations...
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ژورنال
عنوان ژورنال: Sen'i Gakkaishi
سال: 1993
ISSN: 0037-9875,1884-2259
DOI: 10.2115/fiber.49.9_486